G6PD Deficiency

# Makes the RBC membrane friable and leads to episodic hemolytic anemia n jaundice
# Stress (surgery or anesthesia), drugs, newborn period, infection, exposure to fava beans are stimulants/risk factors.
# Culprit drug list is long: vit C n K, Methylene blue (caution in rx of methemoglobinemia),SNP, prilocaine.
Check for anemia, need for transfusion, jaundice(can also appear postop),cataract(increased incidence)
Malignant Hyperthermia has been reported in association
Avoid elective surgeries during a hemolytic episode
Give a folic acid suppliment perioperatively
Paracetamol,Phenytoin,L Dopa etc are safe.

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